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FLUID BALANCE IN CRITICALLY ILL CHILDREN WITH LOWER RESPIRATORY TRACT VIRAL INFECTION: A COHORT STUDY

Chiara Robino

3477471328

BACKGROUND: Increasing evidence has associated poor outcomes of critically ill patients with positive fluid balance. The aim of this study was to explore the pattern of daily fluid balances and their association with outcomes in critically ill children with lower respiratory tract viral infection.

METHODS: a retrospective single center study was conducted, in children supported with high-flow nasal cannula, non-invasive ventilation or invasive ventilation. Median (interquartile range) daily fluid balances, cumulative fluid overload (FO) and peak FO variation over the first week of PICU admission and their association with the duration of respiratory support were assessed.

RESULTS: overall, 94 patients with a median age of 6.9(1.9-18) months, and a respiratory support duration of 4(2-7) days, showed a median (interquartile range) daily fluid balance of 18 (4.5-19.5) ml/kg at day 1, which decreased up to day 3 to 5.9(-14-24.9) ml/kg and increased to 13(-11-29.9) ml/kg at day 7(p=0.001). Median cumulative FO% was 4.6(-0.8 - 11) and peak FO% was 5.7(1.9 – 12.4). Daily fluid balances, calculated according to applied ventilatory support, appeared to be significantly lower in patients requiring mechanical ventilation(p=0.003). No correlation was found between all examined fluid balances and respiratory support duration or oxygen saturation, even after subgroup analysis of patients with invasive mechanical ventilation, or respiratory comorbidities, or bacterial coinfection, or of patients under 1 year old.

CONCLUSIONS: in a cohort of children with bronchiolitis, fluid balance was not associated with duration of respiratory support or other parameters of pulmonary function.

FLUID BALANCE IN CRITICALLY ILL CHILDREN WITH LOWER RESPIRATORY TRACT VIRAL INFECTION: A COHORT STUDY

Orale

G. Toncelli, medico in formazione specialistica U.O. Anestesia e Rianimazione, AOU Meyer - Firenze;

LA. Sorrentino, medico in formazione specialistica, Anestesia e Rianimazione, Università degli studi di Firenze - Firenze

A. Fioccola, medico in formazione specialistica, Anestesia e Rianimazione, Università degli studi di Firenze - Firenze;

B.Tedesco, infermiera di U.O. Anestesia e Rianimazione, AOU Meyer - Firenze

C.Giugni, Dirigente Medico, U.O. Anestesia e Rianimazione, AOU Meyer - Firenze

M. L’Erario, Dirigente Medico, U.O. Anestesia e Rianimazione, AOU Meyer - Firenze

Z. Ricci, Professore Associato, U.O. Anestesia e Rianimazione, AOU Meyer - Firenze

Ricerca

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